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Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis

Abnormal spindle-like microcephaly associated (ASPM) is a causative gene of primary autosomal recessive microcephaly. Microcephaly is considered to be a consequence of a small brain, but the associated molecular mechanisms are not fully understood. In this study, we generated brain-specific Aspm kno...

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Detalles Bibliográficos
Autores principales: Tonosaki, Madoka, Fujimori, Akira, Yaoi, Takeshi, Itoh, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686469/
https://www.ncbi.nlm.nih.gov/pubmed/38019816
http://dx.doi.org/10.1371/journal.pone.0294893