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Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis
Abnormal spindle-like microcephaly associated (ASPM) is a causative gene of primary autosomal recessive microcephaly. Microcephaly is considered to be a consequence of a small brain, but the associated molecular mechanisms are not fully understood. In this study, we generated brain-specific Aspm kno...
Autores principales: | Tonosaki, Madoka, Fujimori, Akira, Yaoi, Takeshi, Itoh, Kyoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686469/ https://www.ncbi.nlm.nih.gov/pubmed/38019816 http://dx.doi.org/10.1371/journal.pone.0294893 |
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