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miRNA cargo in circulating vesicles from neurons is altered in individuals with schizophrenia and associated with severe disease

While RNA expression appears to be altered in several brain disorders, the constraints of postmortem analysis make it impractical for well-powered population studies and biomarker development. Given that the unique molecular composition of neurons are reflected in their extracellular vesicles (EVs),...

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Detalles Bibliográficos
Autores principales: Barnett, Michelle M., Reay, William R., Geaghan, Michael P., Kiltschewskij, Dylan J., Green, Melissa J., Weidenhofer, Judith, Glatt, Stephen J., Cairns, Murray J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686555/
https://www.ncbi.nlm.nih.gov/pubmed/38019909
http://dx.doi.org/10.1126/sciadv.adi4386