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Marginated aberrant red blood cells induce pathologic vascular stress fluctuations in a computational model of hematologic disorders

Red blood cell (RBC) disorders such as sickle cell disease affect billions worldwide. While much attention focuses on altered properties of aberrant RBCs and corresponding hemodynamic changes, RBC disorders are also associated with vascular dysfunction, whose origin remains unclear and which provoke...

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Detalles Bibliográficos
Autores principales: Cheng, Xiaopo, Caruso, Christina, Lam, Wilbur A., Graham, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686556/
https://www.ncbi.nlm.nih.gov/pubmed/38019922
http://dx.doi.org/10.1126/sciadv.adj6423