PI(3,4,5)P3 allosteric regulation of repressor activator protein 1 controls antigenic variation in trypanosomes

African trypanosomes evade host immune clearance by antigenic variation, causing persistent infections in humans and animals. These parasites express a homogeneous surface coat of variant surface glycoproteins (VSGs). They transcribe one out of hundreds of VSG genes at a time from telomeric expressi...

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Detalles Bibliográficos
Autores principales: Touray, Abdoulie O, Rajesh, Rishi, Isebe, Tony, Sternlieb, Tamara, Loock, Mira, Kutova, Oksana, Cestari, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686619/
https://www.ncbi.nlm.nih.gov/pubmed/38019264
http://dx.doi.org/10.7554/eLife.89331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686619/
https://www.ncbi.nlm.nih.gov/pubmed/38019264
http://dx.doi.org/10.7554/eLife.89331

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