Cargando…

PI(3,4,5)P3 allosteric regulation of repressor activator protein 1 controls antigenic variation in trypanosomes

African trypanosomes evade host immune clearance by antigenic variation, causing persistent infections in humans and animals. These parasites express a homogeneous surface coat of variant surface glycoproteins (VSGs). They transcribe one out of hundreds of VSG genes at a time from telomeric expressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Touray, Abdoulie O, Rajesh, Rishi, Isebe, Tony, Sternlieb, Tamara, Loock, Mira, Kutova, Oksana, Cestari, Igor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686619/ https://www.ncbi.nlm.nih.gov/pubmed/38019264 http://dx.doi.org/10.7554/eLife.89331

Ejemplares similares

Codon choice directs constitutive mRNA levels in trypanosomes
por: de Freitas Nascimento, Janaina, et al.
Publicado: (2018)

Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome
por: Armache, Jean Paul, et al.
Publicado: (2019)

The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2
por: Tafur, Lucas, et al.
Publicado: (2019)

Surprising phenotypic diversity of cancer-associated mutations of Gly 34 in the histone H3 tail
por: Lowe, Brandon R, et al.
Publicado: (2021)

ASH1-catalyzed H3K36 methylation drives gene repression and marks H3K27me2/3-competent chromatin
por: Bicocca, Vincent T, et al.
Publicado: (2018)

Interplay between PML NBs and HIRA for H3.3 dynamics following type I interferon stimulus
por: Kleijwegt, Constance, et al.
Publicado: (2023)

H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers
por: Fang, Dong, et al.
Publicado: (2018)

Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3
por: Finogenova, Ksenia, et al.
Publicado: (2020)

Bidirectional regulation of postmitotic H3K27me3 distributions underlie cerebellar granule neuron maturation dynamics
por: Ramesh, Vijyendra, et al.
Publicado: (2023)

RNase III-mediated processing of a trans-acting bacterial sRNA and its cis-encoded antagonist
por: Svensson, Sarah Lauren, et al.
Publicado: (2021)

SET-9 and SET-26 are H3K4me3 readers and play critical roles in germline development and longevity
por: Wang, Wenke, et al.
Publicado: (2018)

H3K9me3 is required for inheritance of small RNAs that target a unique subset of newly evolved genes
por: Lev, Itamar, et al.
Publicado: (2019)

Caenorhabditis elegans nuclear RNAi factor SET-32 deposits the transgenerational histone modification, H3K23me3
por: Schwartz-Orbach, Lianna, et al.
Publicado: (2020)

Structural basis for Scc3-dependent cohesin recruitment to chromatin
por: Li, Yan, et al.
Publicado: (2018)

Gene autoregulation by 3’ UTR-derived bacterial small RNAs
por: Hoyos, Mona, et al.
Publicado: (2020)

Epimutations are associated with CHROMOMETHYLASE 3-induced de novo DNA methylation
por: Wendte, Jered M, et al.
Publicado: (2019)

Telomere repeats induce domains of H3K27 methylation in Neurospora
por: Jamieson, Kirsty, et al.
Publicado: (2018)

ZC3H4 restricts non-coding transcription in human cells
por: Estell, Chris, et al.
Publicado: (2021)

The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome
por: Morrison, Emma A, et al.
Publicado: (2018)

Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction
por: van Weerd, Jan Hendrik, et al.
Publicado: (2020)

How subtle changes in 3D structure can create large changes in transcription
por: Xiao, Jordan Yupeng, et al.
Publicado: (2021)

Tri-methylation of histone H3 lysine 4 facilitates gene expression in ageing cells
por: Cruz, Cristina, et al.
Publicado: (2018)

Independent manipulation of histone H3 modifications in individual nucleosomes reveals the contributions of sister histones to transcription
por: Zhou, Zhen, et al.
Publicado: (2017)

SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program
por: Ratnadiwakara, Madara, et al.
Publicado: (2018)

Phosphorylation of luminal region of the SUN-domain protein Mps3 promotes nuclear envelope localization during meiosis
por: Prasada Rao, Hanumanthu BD, et al.
Publicado: (2021)

3′HS1 CTCF binding site in human β-globin locus regulates fetal hemoglobin expression
por: Himadewi, Pamela, et al.
Publicado: (2021)

Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3′ end biogenesis
por: Muckenfuss, Lena Maria, et al.
Publicado: (2022)

Mcm2 promotes stem cell differentiation via its ability to bind H3-H4
por: Xu, Xiaowei, et al.
Publicado: (2022)

SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans
por: Choi, Charlotte P, et al.
Publicado: (2021)

Promoter-specific changes in initiation, elongation, and homeostasis of histone H3 acetylation during CBP/p300 inhibition
por: Hsu, Emily, et al.
Publicado: (2021)

H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans
por: Huang, Meng, et al.
Publicado: (2022)

Multi-protein bridging factor 1(Mbf1), Rps3 and Asc1 prevent stalled ribosomes from frameshifting
por: Wang, Jiyu, et al.
Publicado: (2018)

Repressive H3K9me2 protects lifespan against the transgenerational burden of COMPASS activity in C. elegans
por: Lee, Teresa Wei-sy, et al.
Publicado: (2019)

Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome
por: Lavery, Laura A, et al.
Publicado: (2020)

Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory
por: Sump, Bethany, et al.
Publicado: (2022)

Histone H3 threonine 11 phosphorylation by Sch9 and CK2 regulates chronological lifespan by controlling the nutritional stress response
por: Oh, Seunghee, et al.
Publicado: (2018)

The E2 Marie Kondo and the CTLH E3 ligase clear deposited RNA binding proteins during the maternal-to-zygotic transition
por: Zavortink, Michael, et al.
Publicado: (2020)

Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling
por: Oh, Seunghee, et al.
Publicado: (2020)

Correction: Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly
por: Shirai, Atsuko, et al.
Publicado: (2017)

STAT3 promotes RNA polymerase III-directed transcription by controlling the miR-106a-5p/TP73 axis
por: Zhang, Cheng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_g39ljvh3o665ngme54sai7hrt2