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The linkage-type and the exchange molecule affect the protein-labeling efficiency of iminoboronate probes

Reversible bioorthogonal conjugation reactions have been exploited in the chemoproteomic field to prepare protein labeling reagents and to visualize labeled proteins. We recently demonstrated that reversible iminoboronates can be used to prepare probes from fragment libraries and that the linkage su...

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Detalles Bibliográficos
Autores principales: van der Zouwen, Antonie J., Jeucken, Aike, van der Pol, Elske, Boerema, Gerben, Slotboom, Dirk J., Witte, Martin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686633/
https://www.ncbi.nlm.nih.gov/pubmed/37947354
http://dx.doi.org/10.1039/d3ob01269g