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Transcriptional Signature of Valproic Acid-Induced Neural Tube Defects in Human Spinal Cord Organoids

In vertebrates, the entire central nervous system is derived from the neural tube, which is formed through a conserved early developmental morphogenetic process called neurulation. Although the perturbations in neurulation caused by genetic or environmental factors lead to neural tube defects (NTDs)...

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Detalles Bibliográficos
Autores principales: Lee, Ju-Hyun, Shaker, Mohammed R., Park, Si-Hyung, Sun, Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686804/
https://www.ncbi.nlm.nih.gov/pubmed/37643760
http://dx.doi.org/10.15283/ijsc23012