Cargando…

Circ_ST6GAL1-mediated competing endogenous RNA network regulates TGF-β1-stimulated matrix Metalloproteinase-13 expression via Runx2 acetylation in osteoblasts

Transforming growth factor-beta1 (TGF-β1) stimulates matrix metalloproteinase-13 (MMP-13, a bone-remodeling gene) expression, and this effect requires p300-mediated Runx2 (Runt-related transcription factor 2) acetylation in osteoblasts. p300 and Runx2 are transcriptional coactivator and bone transcr...

Descripción completa

Detalles Bibliográficos
Autores principales: Saranya, I., Akshaya, R.L., Gomathi, K., Mohanapriya, R., He, Z., Partridge, N.C., Selvamurugan, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686813/
https://www.ncbi.nlm.nih.gov/pubmed/38035043
http://dx.doi.org/10.1016/j.ncrna.2023.11.002