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HIV-1 Env trimers asymmetrically engage CD4 receptors in membranes

Human immunodeficiency virus 1 (HIV-1) infection is initiated by binding of the viral envelope glycoprotein (Env) to the cell-surface receptor CD4(1–4). Although high-resolution structures of Env in a complex with the soluble domains of CD4 have been determined, the binding process is less understoo...

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Detalles Bibliográficos
Autores principales: Li, Wenwei, Qin, Zhuan, Nand, Elizabeth, Grunst, Michael W., Grover, Jonathan R., Bess, Julian W., Lifson, Jeffrey D., Zwick, Michael B., Tagare, Hemant D., Uchil, Pradeep D., Mothes, Walther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686830/
https://www.ncbi.nlm.nih.gov/pubmed/37993716
http://dx.doi.org/10.1038/s41586-023-06762-6