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Antibody fragments functionalized with non-canonical amino acids preserving structure and functionality - A door opener for new biological and therapeutic applications

Functionalization of proteins by incorporating reactive non-canonical amino acids (ncAAs) has been widely applied for numerous biological and therapeutic applications. The requirement not to lose the intrinsic properties of these proteins is often underestimated and not considered. Main purpose of t...

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Detalles Bibliográficos
Autores principales: Hanaee-Ahvaz, Hana, Cserjan-Puschmann, Monika, Mayer, Florian, Tauer, Christopher, Albrecht, Bernd, Furtmüller, Paul G., Wiltschi, Birgit, Hahn, Rainer, Striedner, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686840/
https://www.ncbi.nlm.nih.gov/pubmed/38046162
http://dx.doi.org/10.1016/j.heliyon.2023.e22463