Cargando…

Antibody fragments functionalized with non-canonical amino acids preserving structure and functionality - A door opener for new biological and therapeutic applications

Functionalization of proteins by incorporating reactive non-canonical amino acids (ncAAs) has been widely applied for numerous biological and therapeutic applications. The requirement not to lose the intrinsic properties of these proteins is often underestimated and not considered. Main purpose of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hanaee-Ahvaz, Hana, Cserjan-Puschmann, Monika, Mayer, Florian, Tauer, Christopher, Albrecht, Bernd, Furtmüller, Paul G., Wiltschi, Birgit, Hahn, Rainer, Striedner, Gerald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686840/ https://www.ncbi.nlm.nih.gov/pubmed/38046162 http://dx.doi.org/10.1016/j.heliyon.2023.e22463

Ejemplares similares

Extraction of recombinant periplasmic proteins under industrially relevant process conditions: Selectivity and yield strongly depend on protein titer and methodology
por: Schimek, Clemens, et al.
Publicado: (2020)

Strain specific properties of Escherichia coli can prevent non-canonical amino acid misincorporation caused by scale-related process heterogeneities
por: Mayer, Florian, et al.
Publicado: (2022)

Fast and antibiotic free genome integration into Escherichia coli chromosome
por: Egger, Esther, et al.
Publicado: (2020)

Escherichia coli σ(70) promoters allow expression rate control at the cellular level in genome-integrated expression systems
por: Schuller, Artur, et al.
Publicado: (2020)

Whole cell-based catalyst for enzymatic production of the osmolyte 2-O-α-glucosylglycerol
por: Schwaiger, Katharina N., et al.
Publicado: (2021)

Effects of platelet rich plasma and chondrocyte co-culture on MSC chondrogenesis, hypertrophy and pathological responses
por: Ramezanifard, Rouhallah, et al.
Publicado: (2017)

Fed-batch like cultivation in a micro-bioreactor: screening conditions relevant for Escherichia coli based production processes
por: Toeroek, Csilla, et al.
Publicado: (2015)

High-throughput microbioreactor provides a capable tool for early stage bioprocess development
por: Fink, Mathias, et al.
Publicado: (2021)

CRISPRactivation-SMS, a message for PAM sequence independent gene up-regulation in Escherichia coli
por: Klanschnig, Marco, et al.
Publicado: (2022)

Evaluation of three industrial Escherichia coli strains in fed-batch cultivations during high-level SOD protein production
por: Marisch, Karoline, et al.
Publicado: (2013)

Interaction of Periplasmic Fab Production and Intracellular Redox Balance in Escherichia coli Affects Product Yield
por: Vazulka, Sophie, et al.
Publicado: (2022)

Recombinant Peptide Production Softens Escherichia coli Cells and Increases Their Size during C-Limited Fed-Batch Cultivation
por: Weber, Andreas, et al.
Publicado: (2023)

Neuroregenerative effects of olfactory ensheathing cells transplanted in a multi-layered conductive nanofibrous conduit in peripheral nerve repair in rats
por: Kabiri, Mahboubeh, et al.
Publicado: (2015)

Fusion Tag Design Influences Soluble Recombinant Protein Production in Escherichia coli
por: Köppl, Christoph, et al.
Publicado: (2022)

Cytocompatibility of a conductive nanofibrous carbon nanotube/poly (L-Lactic acid) composite scaffold intended for nerve tissue engineering
por: Kabiri, Mahboubeh, et al.
Publicado: (2015)

Substituting the catalytic proline of 4-oxalocrotonate tautomerase with non-canonical analogues reveals a finely tuned catalytic system
por: Lukesch, Michael S., et al.
Publicado: (2019)

PROFICS: A bacterial selection system for directed evolution of proteases
por: Kröß, Christina, et al.
Publicado: (2021)

Clickable Shiga Toxin B Subunit for Drug Delivery in Cancer Therapy
por: Danielewicz, Natalia, et al.
Publicado: (2023)

Comparative impact of platelet rich plasma and transforming growth factor-β on chondrogenic differentiation of human adipose derived stem cells
por: Hesari, Roya, et al.
Publicado: (2020)

Production of Circularly Permuted Caspase-2 for Affinity Fusion-Tag Removal: Cloning, Expression in Escherichia coli, Purification, and Characterization
por: Cserjan-Puschmann, Monika, et al.
Publicado: (2020)

Open-Door Cervical Laminoplasty with Preservation of Posterior Structures
por: Abdullah, Kalil G., et al.
Publicado: (2012)

Production of full-length SARS-CoV-2 nucleocapsid protein from Escherichia coli optimized by native hydrophobic interaction chromatography hyphenated to multi-angle light scattering detection
por: De Vos, Jelle, et al.
Publicado: (2021)

Engineering cascade biocatalysis in whole cells for bottom-up synthesis of cello-oligosaccharides: flux control over three enzymatic steps enables soluble production
por: Schwaiger, Katharina N., et al.
Publicado: (2022)

Canonical and non-canonical functions of NLRP3
por: Accogli, Théo, et al.
Publicado: (2023)

Residue-Specific Incorporation of the Non-Canonical Amino Acid Norleucine Improves Lipase Activity on Synthetic Polyesters
por: Haernvall, Karolina, et al.
Publicado: (2022)

Editorial: Regulatory T Cell Heterogeneity: Canonical and Non-Canonical Functions
por: Sefik, Esen, et al.
Publicado: (2021)

Plant-Specific Domains and Fragmented Sequences Imply Non-Canonical Functions in Plant Aminoacyl-tRNA Synthetases
por: Saga, Yusuke, et al.
Publicado: (2020)

Performance Analysis of Orthogonal Pairs Designed for an Expanded Eukaryotic Genetic Code
por: Nehring, Sebastian, et al.
Publicado: (2012)

Comparative Effectiveness and Functional Outcome of Open-Door versus French-Door Laminoplasty for Multilevel Cervical Myelopathy: A Meta-Analysis
por: Wiguna, I Gusti Lanang Ngurah Agung Artha, et al.
Publicado: (2019)

Non-canonical vs. Canonical Functions of Heme Oxygenase-1 in Cancer
por: Jagadeesh, Achanta Sri Venakata, et al.
Publicado: (2022)

Reply: From the “Door-to-Antibiotic” to the “Antibiotic-at-Door” Concept?
por: Peltan, Ithan D., et al.
Publicado: (2019)

Generating functions for non canonical maps
por: Vilela-Mendes, R
Publicado: (1986)

The non-canonical functions of the heme oxygenases
por: Vanella, Luca, et al.
Publicado: (2016)

STAT proteins: a kaleidoscope of canonical and non-canonical functions in immunity and cancer
por: Awasthi, Nagendra, et al.
Publicado: (2021)

Canonical and Non-Canonical Functions of the Autophagy Machinery in MHC Restricted Antigen Presentation
por: Münz, Christian
Publicado: (2022)

AGO2 in T-prolymphocytic leukemia: its canonical and non-canonical deregulation and function
por: Braun, Till, et al.
Publicado: (2023)

The open door /
por: Howard, Blanche Willis, 1847-1898
Publicado: (1889)

Hospital Doors
Publicado: (1911)

The Closed Door
Publicado: (1905)

Doors of Hope
Publicado: (1935)

Cannot write session to /tmp/vufind_sessions/sess_ne7499ji680ou5n4va4s5j3kil