Functional analysis of recurrent CDC20 promoter variants in human melanoma

Small nucleotide variants in non-coding regions of the genome can alter transcriptional regulation, leading to changes in gene expression which can activate oncogenic gene regulatory networks. Melanoma is heavily burdened by non-coding variants, representing over 99% of total genetic variation, incl...

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Detalles Bibliográficos
Autores principales: Godoy, Paula M., Oyedeji, Abimbola, Mudd, Jacqueline L., Morikis, Vasilios A., Zarov, Anna P., Longmore, Gregory D., Fields, Ryan C., Kaufman, Charles K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686982/
https://www.ncbi.nlm.nih.gov/pubmed/38030698
http://dx.doi.org/10.1038/s42003-023-05526-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686982/
https://www.ncbi.nlm.nih.gov/pubmed/38030698
http://dx.doi.org/10.1038/s42003-023-05526-2

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