Cargando…

Endosomal Arl4A attenuates EGFR degradation by binding to the ESCRT-II component VPS36

Ligand-induced epidermal growth factor receptor (EGFR) endocytosis followed by endosomal EGFR signaling and lysosomal degradation plays important roles in controlling multiple biological processes. ADP-ribosylation factor (Arf)-like protein 4 A (Arl4A) functions at the plasma membrane to mediate cyt...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Shin-Jin, Lin, Ming-Chieh, Liu, Tsai-Jung, Tsai, Yueh-Tso, Tsai, Ming-Ting, Lee, Fang-Jen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687025/
https://www.ncbi.nlm.nih.gov/pubmed/38030597
http://dx.doi.org/10.1038/s41467-023-42979-9