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Endosomal Arl4A attenuates EGFR degradation by binding to the ESCRT-II component VPS36
Ligand-induced epidermal growth factor receptor (EGFR) endocytosis followed by endosomal EGFR signaling and lysosomal degradation plays important roles in controlling multiple biological processes. ADP-ribosylation factor (Arf)-like protein 4 A (Arl4A) functions at the plasma membrane to mediate cyt...
Autores principales: | Lin, Shin-Jin, Lin, Ming-Chieh, Liu, Tsai-Jung, Tsai, Yueh-Tso, Tsai, Ming-Ting, Lee, Fang-Jen S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687025/ https://www.ncbi.nlm.nih.gov/pubmed/38030597 http://dx.doi.org/10.1038/s41467-023-42979-9 |
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