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An arrayed CRISPR knockout screen identifies genetic regulators of GLUT1 expression

Glucose, a primary fuel source under homeostatic conditions, is transported into cells by membrane transporters such as glucose transporter 1 (GLUT1). Due to its essential role in maintaining energy homeostasis, dysregulation of GLUT1 expression and function can adversely affect many physiological p...

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Detalles Bibliográficos
Autores principales: Shi, Yajuan, Katdare, Ketaki A., Kim, Hyosung, Rosch, Jonah C., Neal, Emma H., Vafaie-Partin, Sidney, Bauer, Joshua A., Lippmann, Ethan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687026/
https://www.ncbi.nlm.nih.gov/pubmed/38030680
http://dx.doi.org/10.1038/s41598-023-48361-5