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Gene interaction network analysis in multiple myeloma detects complex immune dysregulation associated with shorter survival

The plasma cell cancer multiple myeloma (MM) varies significantly in genomic characteristics, response to therapy, and long-term prognosis. To investigate global interactions in MM, we combined a known protein interaction network with a large clinically annotated MM dataset. We hypothesized that an...

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Detalles Bibliográficos
Autores principales: Simhal, Anish K., Maclachlan, Kylee H., Elkin, Rena, Zhu, Jiening, Norton, Larry, Deasy, Joseph O., Oh, Jung Hun, Usmani, Saad Z., Tannenbaum, Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687027/
https://www.ncbi.nlm.nih.gov/pubmed/38030619
http://dx.doi.org/10.1038/s41408-023-00935-2