Phosphorylation of USP27X by GSK3β maintains the stability and oncogenic functions of CBX2

Chromobox protein homolog 2 (CBX2) exerts a multifaceted impact on the progression of aggressive cancers. The proteasome-dependent pathway is crucial for modulating CBX2 regulation, while the specific regulatory roles and mechanisms of deubiquitinating enzymes targeting CBX2 remain poorly understood...

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Detalles Bibliográficos
Autores principales: Xing, Yushu, Ba-tu, Jirimu, Dong, Chongyang, Cao, Xiaodong, Li, Bing, Jia, Xin, Juan, Yu, Lv, Xiaojie, Zhang, Huiwen, Qin, Na, Han, Wuri, Wang, Dongfeng, Qi, Xiao, Wang, Yutong, Hao, Xulu, Zhang, Shuang, Du, Xiaoli, Wang, Huanyun, Wang, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687032/
https://www.ncbi.nlm.nih.gov/pubmed/38030604
http://dx.doi.org/10.1038/s41419-023-06304-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687032/
https://www.ncbi.nlm.nih.gov/pubmed/38030604
http://dx.doi.org/10.1038/s41419-023-06304-y

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