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Chikungunya virus nonstructural protein 1 is a versatile RNA capping and decapping enzyme

Chikungunya virus (CHIKV) nonstructural protein 1 (nsP1) contains both the N7-guanine methyltransferase and guanylyltransferase activities and catalyzes the 5′ end cap formation of viral RNAs. To further understand its catalytic activity and role in virus–host interaction, we demonstrate that purifi...

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Detalles Bibliográficos
Autores principales: Law, Michelle Cheok Yien, Zhang, Kuo, Tan, Yaw Bia, Nguyen, Trinh Mai, Luo, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687048/
https://www.ncbi.nlm.nih.gov/pubmed/37918803
http://dx.doi.org/10.1016/j.jbc.2023.105415