New insights into the downregulation of cytochrome P450 2E1 via nuclear factor κB-dependent pathways in immune-mediated liver injury

The extent of immune-mediated hepatic damage (such as in viral hepatitis) is characterised by the downregulation of cytochrome P450s (CYPs), a class of drug-metabolising enzymes. However, whether this downregulation aids liver cells in maintaining their homeostasis or whether the damage is aggravate...

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Detalles Bibliográficos
Autores principales: Zou, Huiqiong, Cao, Yingying, Hao, Peipei, Jin, Ziqi, Ding, Ruifeng, Bai, Xuefeng, Zhang, Kun, Xue, Yongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687058/
https://www.ncbi.nlm.nih.gov/pubmed/38046176
http://dx.doi.org/10.1016/j.heliyon.2023.e22641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687058/
https://www.ncbi.nlm.nih.gov/pubmed/38046176
http://dx.doi.org/10.1016/j.heliyon.2023.e22641

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