Hydrophobic interaction between the TM1 and H8 is essential for rhodopsin trafficking to vertebrate photoreceptor outer segments

A major unsolved question in vertebrate photoreceptor biology is the mechanism of rhodopsin transport to the outer segment. In rhodopsin-like class A G protein–coupled receptors, hydrophobic interactions between C-terminal α-helix 8 (H8), and transmembrane α-helix-1 (TM1) have been shown to be impor...

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Detalles Bibliográficos
Autores principales: Verma, Dipesh Kumar, Malhotra, Himanshu, Woellert, Torsten, Calvert, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687059/
https://www.ncbi.nlm.nih.gov/pubmed/37918805
http://dx.doi.org/10.1016/j.jbc.2023.105412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687059/
https://www.ncbi.nlm.nih.gov/pubmed/37918805
http://dx.doi.org/10.1016/j.jbc.2023.105412

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