Contribution of pks(+) E. coli mutations to colorectal carcinogenesis

The dominant mutational signature in colorectal cancer genomes is C > T deamination (COSMIC Signature 1) and, in a small subgroup, mismatch repair signature (COSMIC signatures 6 and 44). Mutations in common colorectal cancer driver genes are often not consistent with those signatures. Here we per...

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Detalles Bibliográficos
Autores principales: Chen, Bingjie, Ramazzotti, Daniele, Heide, Timon, Spiteri, Inmaculada, Fernandez-Mateos, Javier, James, Chela, Magnani, Luca, Graham, Trevor A., Sottoriva, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687070/
https://www.ncbi.nlm.nih.gov/pubmed/38030613
http://dx.doi.org/10.1038/s41467-023-43329-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687070/
https://www.ncbi.nlm.nih.gov/pubmed/38030613
http://dx.doi.org/10.1038/s41467-023-43329-5

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