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Contribution of pks(+) E. coli mutations to colorectal carcinogenesis
The dominant mutational signature in colorectal cancer genomes is C > T deamination (COSMIC Signature 1) and, in a small subgroup, mismatch repair signature (COSMIC signatures 6 and 44). Mutations in common colorectal cancer driver genes are often not consistent with those signatures. Here we per...
Autores principales: | Chen, Bingjie, Ramazzotti, Daniele, Heide, Timon, Spiteri, Inmaculada, Fernandez-Mateos, Javier, James, Chela, Magnani, Luca, Graham, Trevor A., Sottoriva, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687070/ https://www.ncbi.nlm.nih.gov/pubmed/38030613 http://dx.doi.org/10.1038/s41467-023-43329-5 |
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