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The dimerized pentraxin-like domain of the adhesion G protein–coupled receptor 112 (ADGRG4) suggests function in sensing mechanical forces

Adhesion G protein–coupled receptors (aGPCRs) feature large extracellular regions with modular domains that often resemble protein classes of various function. The pentraxin (PTX) domain, which is predicted by sequence homology within the extracellular region of four different aGPCR members, is well...

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Detalles Bibliográficos
Autores principales: Kieslich, Björn, Weiße, Renato H., Brendler, Jana, Ricken, Albert, Schöneberg, Torsten, Sträter, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687090/
https://www.ncbi.nlm.nih.gov/pubmed/37863265
http://dx.doi.org/10.1016/j.jbc.2023.105356