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Mitochondrial DNA copy number is associated with Crohn’s disease: a comprehensive Mendelian randomization analysis

Mitochondrial DNA plays a critical role in the pathophysiological process of inflammation. However, the relationship between mitochondrial DNA copy number (mtDNA-CN) and inflammatory bowel diseases (IBD) remains poorly understood. We conducted a comprehensive Mendelian randomization (MR) using three...

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Detalles Bibliográficos
Autores principales: Cai, Xianlei, Li, Xueying, Liang, Chao, Zhang, Miaozun, Xu, Yuan, Dong, Zhebin, Weng, Yihui, Yu, Weiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687096/
https://www.ncbi.nlm.nih.gov/pubmed/38030696
http://dx.doi.org/10.1038/s41598-023-48175-5