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Amplification of poly(I:C)-induced interleukin-6 production in human bronchial epithelial cells by priming with interferon-γ

Proinflammatory cytokine interleukin (IL)-6 was associated with disease severity in patients with COVID-19. The mechanism underlying the excessive IL-6 production by SARS-Cov-2 infection remains unclear. Respiratory viruses initially infect nasal or bronchial epithelial cells that produce various in...

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Detalles Bibliográficos
Autores principales: Okuma, Norikazu, Ito, Masa-aki, Shimizu, Tomoyoshi, Hasegawa, Atsuya, Ohmori, Shin’ya, Yoshida, Kazuki, Matsuoka, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687102/
https://www.ncbi.nlm.nih.gov/pubmed/38030681
http://dx.doi.org/10.1038/s41598-023-48422-9