KRAS4A and KRAS4B in liquid biopsy of metastatic lung adenocarcinoma patients treated with Pembrolizumab or chemotherapy plus Pembrolizumab

KRAS is involved in the stability and expression of PD-L1. We investigated the expression of circulating mRNA (cmRNA) of KRAS4A and KRAS4B and the possible impact on progression-free survival (PFS) of patients with metastatic lung adenocarcinoma treated with immunotherapy. Patients without driver mu...

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Detalles Bibliográficos
Autores principales: Chiari, Rita, Palladino, Silvia, Emili, Rita, De Lisa, Mariagrazia, Sarti, Donatella, Catalano, Vincenzo, Magnani, Mauro, Graziano, Francesco, Ruzzo, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687227/
https://www.ncbi.nlm.nih.gov/pubmed/38030703
http://dx.doi.org/10.1038/s41598-023-48304-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687227/
https://www.ncbi.nlm.nih.gov/pubmed/38030703
http://dx.doi.org/10.1038/s41598-023-48304-0

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