Arsenic trioxide extends survival of Li–Fraumeni syndrome mimicking mouse

Li-Fraumeni syndrome (LFS) is characterized by germline mutations occurring on one allele of genome guardian TP53. It is a severe cancer predisposition syndrome with a poor prognosis, partly due to the frequent development of subsequent primary tumors following DNA-damaging therapies. Here we explor...

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Detalles Bibliográficos
Autores principales: Li, Jiabing, Xiao, Shujun, Shi, Fangfang, Song, Huaxin, Wu, Jiaqi, Zheng, Derun, Chen, Xueqin, Tan, Kai, Lu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687230/
https://www.ncbi.nlm.nih.gov/pubmed/38030599
http://dx.doi.org/10.1038/s41419-023-06281-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687230/
https://www.ncbi.nlm.nih.gov/pubmed/38030599
http://dx.doi.org/10.1038/s41419-023-06281-2

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