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Arsenic trioxide extends survival of Li–Fraumeni syndrome mimicking mouse

Li-Fraumeni syndrome (LFS) is characterized by germline mutations occurring on one allele of genome guardian TP53. It is a severe cancer predisposition syndrome with a poor prognosis, partly due to the frequent development of subsequent primary tumors following DNA-damaging therapies. Here we explor...

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Detalles Bibliográficos
Autores principales:	Li, Jiabing, Xiao, Shujun, Shi, Fangfang, Song, Huaxin, Wu, Jiaqi, Zheng, Derun, Chen, Xueqin, Tan, Kai, Lu, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687230/ https://www.ncbi.nlm.nih.gov/pubmed/38030599 http://dx.doi.org/10.1038/s41419-023-06281-2

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