Evaluating the stability of host-reference gene expression and simultaneously quantifying parasite burden and host immune responses in murine malaria

The efficacy of pre-erythrocytic stage malaria antigens or vaccine platforms is routinely assessed in murine models challenged with Plasmodium sporozoites. Relative liver-stage parasite burden is quantified using reverse transcription quantitative PCR (RTqPCR), which relies on constitutively express...

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Detalles Bibliográficos
Autores principales: Browne, Daniel J., Kelly, Ashton M., Brady, Jamie, Proietti, Carla, Sarathkumara, Yomani D., Pattinson, David J., Doolan, Denise L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687243/
https://www.ncbi.nlm.nih.gov/pubmed/38030676
http://dx.doi.org/10.1038/s41598-023-48066-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687243/
https://www.ncbi.nlm.nih.gov/pubmed/38030676
http://dx.doi.org/10.1038/s41598-023-48066-9

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