Correcting modification-mediated errors in nanopore sequencing by nucleotide demodification and reference-based correction

The accuracy of Oxford Nanopore Technology (ONT) sequencing has significantly improved thanks to new flowcells, sequencing kits, and basecalling algorithms. However, novel modification types untrained in the basecalling models can seriously reduce the quality. Here we reports a set of ONT-sequenced...

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Detalles Bibliográficos
Autores principales: Chiou, Chien-Shun, Chen, Bo-Han, Wang, You-Wun, Kuo, Nang-Ting, Chang, Chih-Hsiang, Huang, Yao-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687267/
https://www.ncbi.nlm.nih.gov/pubmed/38030695
http://dx.doi.org/10.1038/s42003-023-05605-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687267/
https://www.ncbi.nlm.nih.gov/pubmed/38030695
http://dx.doi.org/10.1038/s42003-023-05605-4

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