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Correcting modification-mediated errors in nanopore sequencing by nucleotide demodification and reference-based correction
The accuracy of Oxford Nanopore Technology (ONT) sequencing has significantly improved thanks to new flowcells, sequencing kits, and basecalling algorithms. However, novel modification types untrained in the basecalling models can seriously reduce the quality. Here we reports a set of ONT-sequenced...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687267/ https://www.ncbi.nlm.nih.gov/pubmed/38030695 http://dx.doi.org/10.1038/s42003-023-05605-4 |