Studies on solubility measurement of codeine phosphate (pain reliever drug) in supercritical carbon dioxide and modeling

In this study, the solubilities of codeine phosphate, a widely used pain reliever, in supercritical carbon dioxide (SC-CO(2)) were measured under various pressures and temperature conditions. The lowest determined mole fraction of codeine phosphate in SC-CO(2) was 1.297 × 10(−5) at 308 K and 12 MPa,...

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Detalles Bibliográficos
Autores principales: Sodeifian, Gholamhossein, Garlapati, Chandrasekhar, Arbab Nooshabadi, Maryam, Razmimanesh, Fariba, Roshanghias, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687273/
https://www.ncbi.nlm.nih.gov/pubmed/38030705
http://dx.doi.org/10.1038/s41598-023-48234-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687273/
https://www.ncbi.nlm.nih.gov/pubmed/38030705
http://dx.doi.org/10.1038/s41598-023-48234-x

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