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Studies on solubility measurement of codeine phosphate (pain reliever drug) in supercritical carbon dioxide and modeling
In this study, the solubilities of codeine phosphate, a widely used pain reliever, in supercritical carbon dioxide (SC-CO(2)) were measured under various pressures and temperature conditions. The lowest determined mole fraction of codeine phosphate in SC-CO(2) was 1.297 × 10(−5) at 308 K and 12 MPa,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687273/ https://www.ncbi.nlm.nih.gov/pubmed/38030705 http://dx.doi.org/10.1038/s41598-023-48234-x |