Pharmacokinetics of a Modified-Release Dexamphetamine Sulfate Formulation Following Single and Multiple Dosing in Healthy Adults: Comparative Bioavailability with Immediate-Release Dexamphetamine Sulfate, between Strengths, Assessment of Food and Meal Composition Effects

BACKGROUND: A modified-release dexamphetamine sulfate formulation (DEX-MR) is under development for the treatment of attention-deficit/hyperactivity disorder. OBJECTIVE: We investigated the bioequivalence of once-daily DEX-MR to twice-daily immediate-release dexamphetamine sulfate (DEX-IR) after sin...

Descripción completa

Detalles Bibliográficos
Autores principales: Sandersleben, Henrik Uebel-von, Mayer, Anke, Ruhmann, Michaela, Dangel, Oliver, Schütz, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687392/
https://www.ncbi.nlm.nih.gov/pubmed/38033826
http://dx.doi.org/10.2478/sjcapp-2023-0014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687392/
https://www.ncbi.nlm.nih.gov/pubmed/38033826
http://dx.doi.org/10.2478/sjcapp-2023-0014

Ejemplares similares