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Pharmacokinetics of a Modified-Release Dexamphetamine Sulfate Formulation Following Single and Multiple Dosing in Healthy Adults: Comparative Bioavailability with Immediate-Release Dexamphetamine Sulfate, between Strengths, Assessment of Food and Meal Composition Effects

BACKGROUND: A modified-release dexamphetamine sulfate formulation (DEX-MR) is under development for the treatment of attention-deficit/hyperactivity disorder. OBJECTIVE: We investigated the bioequivalence of once-daily DEX-MR to twice-daily immediate-release dexamphetamine sulfate (DEX-IR) after sin...

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Detalles Bibliográficos
Autores principales:	Sandersleben, Henrik Uebel-von, Mayer, Anke, Ruhmann, Michaela, Dangel, Oliver, Schütz, Helmut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sciendo 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687392/ https://www.ncbi.nlm.nih.gov/pubmed/38033826 http://dx.doi.org/10.2478/sjcapp-2023-0014

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