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Oncostatin M suppresses IL31RA expression in dorsal root ganglia and interleukin-31-induced itching

BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by intermittent itchy rash. Type 2 inflammatory cytokines such as interleukin (IL)-4, IL-13, and IL-31 are strongly implicated in AD pathogenesis. Stimulation of IL-31 cognate receptors on C-fiber nerve endings i...

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Detalles Bibliográficos
Autores principales: Suehiro, Masataka, Numata, Tomofumi, Saito, Ryo, Yanagida, Nozomi, Ishikawa, Chie, Uchida, Kazue, Kawaguchi, Tomoko, Yanase, Yuhki, Ishiuji, Yozo, McGrath, John, Tanaka, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687395/
https://www.ncbi.nlm.nih.gov/pubmed/38035099
http://dx.doi.org/10.3389/fimmu.2023.1251031