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LRPAP1 is released from activated microglia and inhibits microglial phagocytosis and amyloid beta aggregation

Low-density lipoprotein receptor-related protein-associated protein 1 (LRPAP1), also known as receptor associated protein (RAP), is an endoplasmic reticulum (ER) chaperone and inhibitor of LDL receptor related protein 1 (LRP1) and related receptors. These receptors have dozens of physiological ligan...

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Detalles Bibliográficos
Autores principales: Reid, Kyle M., Brown, Guy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687467/
https://www.ncbi.nlm.nih.gov/pubmed/38035103
http://dx.doi.org/10.3389/fimmu.2023.1286474