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Conditional knockout of REST/NRSF in excitatory neurons reduces seizure susceptibility to chemical kindling

The repressor element-1 silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) is an epigenetic master regulator that plays a crucial role during nervous system development and maturation. REST function was originally described during development, where it determines neuronal...

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Detalles Bibliográficos
Autores principales: Natali, Giulia, Michetti, Caterina, Krawczun-Rygmaczewska, Alicja, Floss, Thomas, Cesca, Fabrizia, Benfenati, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687554/
https://www.ncbi.nlm.nih.gov/pubmed/38034589
http://dx.doi.org/10.3389/fncel.2023.1267609