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Muscarinic acetylcholine receptors M(2) are upregulated in the atrioventricular nodal tract in horses with a high burden of second-degree atrioventricular block

BACKGROUND: Second-degree atrioventricular (AV) block at rest is very common in horses. The underlying molecular mechanisms are unexplored, but commonly attributed to high vagal tone. AIM: To assess whether AV block in horses is due to altered expression of the effectors of vagal signalling in the A...

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Detalles Bibliográficos
Autores principales: Nissen, Sarah Dalgas, Saljic, Arnela, Carstensen, Helena, Braunstein, Thomas Hartig, Hesselkilde, Eva Melis, Kjeldsen, Sofie Troest, Hopster-Iversen, Charlotte, D’Souza, Alicia, Jespersen, Thomas, Buhl, Rikke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687567/
https://www.ncbi.nlm.nih.gov/pubmed/38034369
http://dx.doi.org/10.3389/fcvm.2023.1102164