Improved production of Taxol(®) precursors in S. cerevisiae using combinatorial in silico design and metabolic engineering

BACKGROUND: Integrated metabolic engineering approaches that combine system and synthetic biology tools enable the efficient design of microbial cell factories for synthesizing high-value products. In this study, we utilized in silico design algorithms on the yeast genome-scale model to predict geno...

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Detalles Bibliográficos
Autores principales: Malcı, Koray, Santibáñez, Rodrigo, Jonguitud-Borrego, Nestor, Santoyo-Garcia, Jorge H., Kerkhoven, Eduard J., Rios-Solis, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687855/
https://www.ncbi.nlm.nih.gov/pubmed/38031061
http://dx.doi.org/10.1186/s12934-023-02251-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687855/
https://www.ncbi.nlm.nih.gov/pubmed/38031061
http://dx.doi.org/10.1186/s12934-023-02251-7

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