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Single-cell analysis unveils activation of mast cells in colorectal cancer microenvironment

The role of mast cells (MCs) in colorectal cancer (CRC) remains unclear, and a comprehensive single-cell study on CRC MCs has not been conducted. This study used a multi-omics approach, integrating single-cell sequencing, spatial transcriptomics, and bulk tissue sequencing data to investigate the he...

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Detalles Bibliográficos
Autores principales: Xie, Zhenyu, Niu, Liaoran, Zheng, Gaozan, Du, Kunli, Dai, Songchen, Li, Ruikai, Dan, Hanjun, Duan, Lili, Wu, Hongze, Ren, Guangming, Dou, Xinyu, Feng, Fan, Zhang, Jian, Zheng, Jianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10687892/
https://www.ncbi.nlm.nih.gov/pubmed/38031173
http://dx.doi.org/10.1186/s13578-023-01144-x