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Insights into the Mechanism of Tryptophan Fluorescence Quenching due to Synthetic Crowding Agents: A Combined Experimental and Computational Study

[Image: see text] Intrinsic tryptophan fluorescence spectroscopy is an important tool for examining the effects of molecular crowding and confinement on the structure, dynamics, and function of proteins. Synthetic crowders such as dextran, ficoll, polyethylene glycols, polyvinylpyrrolidone, and thei...

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Detalles Bibliográficos
Autores principales: Fossum, Carl J., Johnson, Benjamin O. V., Golde, Spencer T., Kielman, Alexis J., Finke, Brianna, Smith, Macey A., Lowater, Harrison R., Laatsch, Bethany F., Bhattacharyya, Sudeep, Hati, Sanchita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688029/
https://www.ncbi.nlm.nih.gov/pubmed/38046287
http://dx.doi.org/10.1021/acsomega.3c06006