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Exploring the Staphylococcus aureus Gyrase Complex and Human Topoisomerase: Potential Target for Molecular Docking and Biological Studies with Substituted Polychloroaniline

[Image: see text] This paper targets the nuclease activity of polymeric chemical compounds toward bacterial genomic DNA and also elucidates their probable drug-like properties against the enzymes bacterial gyrase complex and human topoisomerase. Poly-o-chloroaniline, poly-m-chloroaniline, and poly-o...

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Detalles Bibliográficos
Autores principales: Tomar, Richa, Sarkar, Paratpar, Srivastava, Vivek, Gupta, Pankaj, Malik, Sumira, Khan, Azmat Ali, Tambuwala, Murtaza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688032/
https://www.ncbi.nlm.nih.gov/pubmed/38046322
http://dx.doi.org/10.1021/acsomega.3c05970