Dihydroartemisinin-Ursodeoxycholic Bile Acid Hybrids in the Fight against SARS-CoV-2

[Image: see text] Here, we propose the molecular hybridization of dihydroartemisinin (DHA) and ursodeoxycholic bile acid (UDCA), approved drugs, for the preparation of antiviral agents against SARS-CoV-2. DHA and UDCA were selected on the basis of their recently demonstrated in vitro activity agains...

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Detalles Bibliográficos
Autores principales: Marchesi, Elena, Gentili, Valentina, Bortolotti, Daria, Preti, Lorenzo, Marchetti, Paolo, Cristofori, Virginia, Fantinati, Anna, Rizzo, Roberta, Trapella, Claudio, Perrone, Daniela, Navacchia, Maria Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688034/
https://www.ncbi.nlm.nih.gov/pubmed/38046338
http://dx.doi.org/10.1021/acsomega.3c07034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688034/
https://www.ncbi.nlm.nih.gov/pubmed/38046338
http://dx.doi.org/10.1021/acsomega.3c07034

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