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An intronic LINE-1 regulates IFNAR1 expression in human immune cells

BACKGROUND: Despite their origins as selfish parasitic sequences, some transposons in the human genome have been co-opted to serve as regulatory elements, contributing to the evolution of transcriptional networks. Most well-characterized examples of transposon-derived regulatory elements derive from...

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Detalles Bibliográficos
Autores principales: Buttler, Carmen A., Ramirez, Daniel, Dowell, Robin D., Chuong, Edward B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688052/
https://www.ncbi.nlm.nih.gov/pubmed/38037122
http://dx.doi.org/10.1186/s13100-023-00308-3