The SMYD3-dependent H3K4me3 status of IGF2 intensifies local Th2 differentiation in CRSwNP via positive feedback

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous and common upper airway disease divided into various inflammatory endotypes. Recent epidemiological findings showed a T helper 2 (Th2)-skewed dominance in CRSwNP patients. Histone modification alterations can regulate transcription...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Wei, Yi, Lu, Tong, Li, Zhengqi, Lai, Shimin, Yan, Yan, Chen, Changhui, Wen, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688075/
https://www.ncbi.nlm.nih.gov/pubmed/38037054
http://dx.doi.org/10.1186/s12964-023-01375-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688075/
https://www.ncbi.nlm.nih.gov/pubmed/38037054
http://dx.doi.org/10.1186/s12964-023-01375-y

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