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Direct 3D Sampling of the Embryonic Mouse Head: Layer-wise Nanosecond Infrared Laser (NIRL) Ablation from Scalp to Cortex for Spatially Resolved Proteomics

[Image: see text] Common workflows in bottom-up proteomics require homogenization of tissue samples to gain access to the biomolecules within the cells. The homogenized tissue samples often contain many different cell types, thereby representing an average of the natural proteome composition, and ra...

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Detalles Bibliográficos
Autores principales: Navolić, Jelena, Moritz, Manuela, Voß, Hannah, Schlumbohm, Simon, Schumann, Yannis, Schlüter, Hartmut, Neumann, Julia E., Hahn, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688223/
https://www.ncbi.nlm.nih.gov/pubmed/37956982
http://dx.doi.org/10.1021/acs.analchem.3c02637