Cargando…

Coiled-coil-mediated dimerization of Atg16 is required for binding to the PROPPIN Atg21

PROPPINs/WIPIs are β-propeller proteins that bind phosphoinositides and contribute to the recruitment of protein complexes involved in membrane remodelling processes such as autophagosome formation and endosomal trafficking. Yeast Atg21 and mammalian WIPI2 interact with Atg16/ATG16L1 to mediate recr...

Descripción completa

Detalles Bibliográficos
Autores principales: Bueno-Arribas, Miranda, Cruz-Cuevas, Celia, Navas, María-Angeles, Escalante, Ricardo, Vincent, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688262/
https://www.ncbi.nlm.nih.gov/pubmed/37989223
http://dx.doi.org/10.1098/rsob.230192