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Coiled-coil-mediated dimerization of Atg16 is required for binding to the PROPPIN Atg21
PROPPINs/WIPIs are β-propeller proteins that bind phosphoinositides and contribute to the recruitment of protein complexes involved in membrane remodelling processes such as autophagosome formation and endosomal trafficking. Yeast Atg21 and mammalian WIPI2 interact with Atg16/ATG16L1 to mediate recr...
Autores principales: | Bueno-Arribas, Miranda, Cruz-Cuevas, Celia, Navas, María-Angeles, Escalante, Ricardo, Vincent, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10688262/ https://www.ncbi.nlm.nih.gov/pubmed/37989223 http://dx.doi.org/10.1098/rsob.230192 |
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